Minimally Invasive Surfactant Therapy: New Age

Update of minimally invasive surfactant therapy

To date, preterm infants with respiratory distress syndrome (RDS) after birth have been managed with a combination of endotracheal intubation, surfactant instillation, and mechanical ventilation. It is now recognized that noninvasive ventilation (NIV) such as nasal continuous positive airway pressure (CPAP) in preterm infants is a reasonable alternative to elective intubation after birth. Recen...

Innovation in surfactant therapy I: surfactant lavage and surfactant administration by fluid bolus using minimally invasive techniques.

Innovation in the field of exogenous surfactant therapy continues more than two decades after the drug became commercially available. One such innovation, lung lavage using dilute surfactant, has been investigated in both laboratory and clinical settings as a treatment for meconium aspiration syndrome (MAS). Studies in animal models of MAS have affirmed that dilute surfactant lavage can remove ...

Image-guided Minimally Invasive Therapy

Non-Invasive Ventilation and Surfactant Therapy

The lungs of premature infants are more vulnerable than term infants to the effects of invasive positive pressure ventilation. Published literature supporting the use of non-invasive respiratory support with CPAP, bi-level CPAP mode, such as, SiPAP and Nasal Intermittent Positive Pressure Ventilation (NIPPV), and surfactant administration strategies are discussed. This review focuses on non-inv...

Minimally Invasive Surgical Technique in Periodontal Therapy

sites.1 But the traditionally practiced periodontal surgical techniques were designed for the treatment of generalized disease,2 which involves relatively long incision and extension into non-periodontally involved areas. These extensive tissue reflections could result in attachment loss3 and can lead to morbidities like thermal sensitivity, food impaction, and compromised esthetics.4 In recent...